Infection: LO: Describe The Main Routes Pathogens Take Into The Body, and Describe The Non-Immune Response

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Infection

LO : Describe the main routes pathogens take into the body, and describe the non-immune response.

Game Time!

SPLAT

POST IT

Taboo

How are pathogens communicable?


Vectors (living organisms such as mosquito malaria) Fomites (towel in hospital MRSA) Direct Contact (genitals gonorrhoea)

Inhalation ( breathing T.B.)


Ingestion (diet salmonella) Inoculation (break in skin HIV)

Lets get SILLY!

Read p92 Group A : Vectors & Inhalation Group B : Fomites & Ingestion Group C : Direct Contact & Inoculation

Barriers to Entry

The body has a range of defences to harmful pathogens

before action of the immune system is needed

Skin

Skin is impenetrable layer toughened

by keratin, which protects tissue underneath.


Secretes Sebum which contains

chemicals that inhibit the growth of micro-organisms.


Natural skin flora competition

Washing too often can be bad for you!

Internal Epithelial Cells

Produce mucus to trap

pathogens
Mucus contains lysozymes,

enzyme which destroys bacterial cell walls.


Lysozymes very effective with

gram + bacteria, as they break down exposed peptidoglycan.


Tears also contain lysozymes

More Internal Epithelial

Gut

Saliva is bactericidal :

destroy bacteria or slow growth


Stomach acid Competition with gut flora Vomiting

Poster Time
Read p93/94 On your human body

explain the physical barriers to pathogen entry.

TASK/HOMEWORK

Read HSW box on p95 Do you think there methods were unorthodox? Why? Answer Q1-3 on p95 in detail (this will be marked,

handed in tomorrow)

PLENARY

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