Should Know About Surgical Should Know About Surgical
Pathology Pathology Jose Ma. C. Avila, M.D. Jose Ma. C. Avila, M.D. Medical Center Manila Medical Center Manila What is Surgical Pathology? What is Surgical Pathology? Surgical Pathology is the.. Surgical Pathology is the.. Pathology specialties: Pathology specialties: Anatomic Pathology Anatomic Pathology Clinical Pathology Clinical Pathology Scope of Surgical Pathology Scope of Surgical Pathology Routine tissue biopsies, excisions, Routine tissue biopsies, excisions, operative procedures operative procedures Frozen section diagnosis (rapid) Frozen section diagnosis (rapid) Cytology Cytology Effusions, exudations, other body fluids Effusions, exudations, other body fluids FNAB (palpable, CTguided, UTSguided) FNAB (palpable, CTguided, UTSguided) Special Procedures Special Procedures mmunohistochemistry: ERA, PRN, Her2Neu, mmunohistochemistry: ERA, PRN, Her2Neu, other other Histochemistry: Giemsa Histochemistry: Giemsa Surgical Pathology in MCM Surgical Pathology in MCM Tissue processing (routine) Tissue processing (routine) Special immunohistochemistry (ERA, Special immunohistochemistry (ERA, PRN, C PRN, C- -ERB ERB- -2, CYTOKERATN, EMA) 2, CYTOKERATN, EMA) Frozen section diagnosis Frozen section diagnosis Routine cytology (smears, cell block) Routine cytology (smears, cell block) Giemsa for H. pylori demonstration Giemsa for H. pylori demonstration Bone marrow core biopsy decalcification Bone marrow core biopsy decalcification What is my role as a medical What is my role as a medical intern? intern? Labelling Labelling Fixation Fixation Clinicopathologic correlation Clinicopathologic correlation Communication Communication Fixation of Specimens Fixation of Specimens Crucial step Crucial step 10% formalin 10% formalin 95% ethyl alcohol 95% ethyl alcohol No fixation if for frozen section No fixation if for frozen section Fillling up the Request Form Fillling up the Request Form Full name and age/sex of patient Full name and age/sex of patient Organ submitted and side if appropriate Organ submitted and side if appropriate Type of procedure done Type of procedure done Pertinent Clinical Data and Diagnosis Pertinent Clinical Data and Diagnosis Other things expected to be resolved by Other things expected to be resolved by the pathologist the pathologist For requests outside MCM For requests outside MCM Paraffin blocks needed with slides Paraffin blocks needed with slides Best block with tumor chosen Best block with tumor chosen No completion procedures please! Tumor No completion procedures please! Tumor may not be there. may not be there. Decalcification Decalcification Acid used (nitric) Acid used (nitric) Core marrow biopsy or bony hard Core marrow biopsy or bony hard specimens specimens May take days or even weeks depending May take days or even weeks depending on the hardness of the specimen on the hardness of the specimen H. Pylori demonstration H. Pylori demonstration in gastric biopsies in gastric biopsies Cytology preparation Cytology preparation Equal volume of 95% ethyl alcohol for Equal volume of 95% ethyl alcohol for body fluids body fluids mmediate fixation for Pap smear (wet mmediate fixation for Pap smear (wet fixation) and FNAB slides fixation) and FNAB slides Difficult cases Difficult cases Specialty consultation Specialty consultation Deeper cuts or Thinner Cuts or even Deeper cuts or Thinner Cuts or even Recuts Recuts Pathologists are not machines reading Pathologists are not machines reading your slides and referrals your slides and referrals Poor preparation or scanty material may Poor preparation or scanty material may be responsible for difficulties in diagnosis be responsible for difficulties in diagnosis Clinicopathologic correlation Clinicopathologic correlation