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Slide Lab 2 (Keratosis)
Slide Lab 2 (Keratosis)
White Patches
Debris
Hyperkeratosis
orthokeratin
Atrophy Acanthosis
Dysplasia
Hyperkeratosis
-Intracellular
Aspirin burn.
Leukoplakia
Homogenous Leukoplakia
Homogeneous - flat, uniform, predominantly white plaques - may show shallow cracks/fissures
Speckeled Speckeled
Erythroplakia
2. increased melanin production in basal keratinocytes and leakage of melanin into the underlying connective tissue (melanin incontinence).
Regezi
Reticular pattern
Erosive/atrophic types
OrthoOrtho- or parakeratosis. Epithelial atrophy or acanthosis (sawtooth pattern of rete ridges). Dense, well-defined band of wellsubepithelial mononuclear infiltrate, mainly T-cells. T-
Liquefactive degeneration of basal cell layer associated with edema and lymphocytic infiltration. Civatte bodies: hyaline shrunken bodies representing apoptotic cells.
Basal cell degeneration may result in subepithelial bullae formation and ulceration.