Automated Analysis of Auditory Brainstem Evoked Response using Wavelets And Neural Networks

BY JYOTHI.B ASST.PROFF, DEPT.OF E&C, NIE-IT, MYSORE GUIDED BY Dr. V. UDAYASHANKARA PROF. DEPT OF IT,SJCE MYSORE
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CONTENTS Introduction Algorithm

Implementation
Results

Conclusion
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INTRODUCTION

What is Brainstem Evoked Response Audiometry(BERA)? What is the principle? What are its applications?

 Brainstem response is Electrical signal evoked in human Brainstem due to presentation of sound such as click or tone. Brainstem Evoked Response Audiometry is a screening test to monitor the Hearing loss or Deafness in a patient .

BLOCK DIAGRAM

CLINICAL APPLICATIONS

Estimation of threshold
Investigation of hearing loss

TYPICAL BERA WAVEFORM

ORIGIN OF EACH WAVE:

PEAK I II III IV V VI VII
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ORIGIN Cochlear nerve Dorsal & Ventral cochlear nucleus Superior olivary complex Nucleus of lateral lemniscus Inferior colliculus Medial geniculate body Auditory radiation(cortex

OBJECTIVE :

The aim of this paper is

to develop software

classification model to assist the audiologist with

an automated detection of the ABR waveform and

also detection of peaks for identification of

pathologies.
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ALGORITHM:

Extraction of BERA from recorded EEG

Identification of peaks Classification

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FLOW CHART

Get the EEG Data

Is a BERA response present

no

Identification of peaks

Peak detection

Classification Normal 11 Abnormal

IMPLEMENTATION: Data Acquisition: EEG data is collected in JSS hospital and data base is created which consists of 30 normal (neonates)and 25 abnormal patients..

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EXTRACTION:
Band pass filtering with cut-off freq. 30-3000 Hz. Signal adaptive filtering using complex wavelets

This algorithm uses Dual tree complex wavelet

transform.
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PEAK IDENTIFICATION

Gaussian Derivative estimation filter used Steps :

Find Zero Crossings and

Peak Detection using Local Max And Min Value. Finally Peak Labeling.
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FLOW CHART:

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PARAMETERS USED FOR LABELING PEAKS

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CLASSIFICATION :

Artificial Neural Network(ANN) is used . Diagnosis of hearing disorder is one of the applications of neural network.

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 ANN is defined by 3 types of parameters:

1. Inter connection pattern layers of neurons.nonlinear 2. Learning process for updating weights 3. The activation function

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FEED-FORWARD ARCHITECTURE

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BLOCK DIAGRAM

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LEARNING ALGORITHM :

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PATIENT INFORMATION
Intensity Ear peak I Amplitude of Peak I peak III Amplitude of peak III peak V Amplitude of peak V Inter peak (I III) Inter peak (III V) Inter peak (I V)

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RESULT:
1. If the output node value is >0.7467 --- Normal
2. Else if output node value is <= 0.7467 --- Abnormal

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TESTS AND RESULTS:

10000

5000

-5000 0 x 10
4

100

200

300

400

500

600

700

800

Complex 1-D wavelet

1 0.5

(t)

0 -0.5 -1

100

200

300 t

400

500

600

25 Fig: Extracted BERA signal

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Fig: Gaussian First Derivative:

First Derivative 3

Amplitude

-1

-2

-3

-4 -15

-10

-5

0 Time

10

15

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Fig: First deriv. of the Input signal

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Fig: Zero crossing & peak identification

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Fig: Peak Labeled

GUI in MATLAB :

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GUI in C:

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ANN RESULTS:
Normal
Training Number 30

Abnormal
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Test Number
Correct Classification Rate of classification

25
24 96%

20
18 90%

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Accuracy of ANN classification

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CONCLUSION
This paper demonstrates the feasibility of an algorithm for extraction of clean BAER waveforms and subsequent automatic peak identification in order to perform functional assessment of the brainstem. Automated method gives 96% for normal 90% Accuracy for Abnormal patients.

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REFERENCES:

[1]A. Jacquin, E. Causevic, E. R. John, and L. S. Prichep, Optimal denoising of brainstem auditory evoked response (BAER) for automatic peak identi- fication and brainstem assessment, in Proc. 28th IEEE [2]A. Jacquin, E. Causevic, E.R. John, J. Kovacevic Adaptive complex wavelet-based filtering of EEG for extraction of evoked potential responses, ICASSP04, 2004. [3]Automated Analysis of the Auditory Brainstem Response Using Derivative Estimation Wavelets Andrew P. Bradleya, Wayne J. Wilsonb [4]Hall III, J., Handbook of auditory evoked responses,Needham Heights, Massachusetts: Allyn and Bacon,1992. [5] Mallat, S.G., A Wavelet tour of signal processing,2nd Ed., San Diego: Academic Press, 1999. 37

THANK U

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