Professional Documents
Culture Documents
Lecture 11a
Lecture 11a
Osteoarthritis (OA)
OA is the most common form of arthritis and the most common joint disease Most common age group : more than age 45 women are more commonly affected than men. OA most common sites ends of the fingers i.e. PIP & DIP , neck, lower back, knees, and hips.
OA
OA is a disease of joints that affects all of the weight-bearing components of the joint:
OA
Nodal osteoarthritis Note bony enlargement of distal and proximal interphalangeal joints (Heberden's nodes and Bouchard's nodes, respectively).
OA Risk Factors
Age
Age is the strongest risk factor for OA. Although OA can start in young adulthood, if you are over 45 years old, you are at higher risk.
Female gender
In general, arthritis occurs more frequently in women than in men. Before age 45, OA occurs more frequently in men; after age 45, OA is more common in women. OA of the hand is particularly common among women.
People with joints that move or fit together incorrectly, such as bow legs, a dislocated hip are more likely to develop OA in those joints.
Joint alignment
OA Risk Factors
Hereditary gene defect
A defect in one of the genes responsible for the cartilage component collagen can cause deterioration of cartilage.
Traumatic injury (ex. Ligament or meniscal tears) to the knee or hip increases your risk for developing OA in these joints. Joints that are used repeatedly in certain jobs may be more likely to develop OA because of injury or overuse. Being overweight during midlife or the later years is among the strongest risk factors for OA of the knee.
Obesity
OA Symptoms
OA usually occurs slowly It may be many years before the damage to the joint becomes noticeable Only a third of people whose X-rays show OA report pain or other symptoms:
Steady or intermittent pain in a joint Stiffness that tends to follow periods of inactivity, such as sleep or sitting Swelling or tenderness in one or more joints [not necessarily occurring on both sides of the body at the same time] Crunching feeling or sound of bone rubbing on bone (called crepitus) when the joint is used
The repair mechanisms of tissue absorption and synthesis get out of balance and result in osteophyte formation (bone spurs) and bone cysts
OA Articular Cartilage
Articular cartilage is the main tissue affected
OA results in: Increased tissue swelling Change in color Cartilage fibrillation Cartilage erosion down to subchondral bone
OA Articular Cartilage
OA Articular Cartilage
Proteoglycan loss results in an inability to hold on to water content: - Decreased resistance to compression especially with repeated stress
OA Radiographic Diagnosis
OA Radiographic Diagnosis
Asymmetrical joint space narrowing
Periarticular sclerosis
Osteophytes
Sub-chrondral bone cysts
OA Arthroscopic Diagnosis
Arthroscopy allows earlier diagnosis by demonstrating the more subtle cartilage changes that are not visible on x-ray
Normal Articular Cartilage Ostearthritic degenerated cartilage with exposed subchondral bone
OA Arthroscopic Treatment
In addition to being the most accurate way of determining how advanced the osteoarthritis is: Arthroscopy also ALLOWS THE SURGEON TO DEBRIDE THE KNEE JOINT
Debridement essentially consists of cleaning out the joint of all debris and loose fragments. During the debridment ANY LOOSE FRAGMENTS OF CARTILAGE ARE REMOVED and the KNEE IS WASHED WITH A SALINE SOLUTION. The areas of the knee joint which are badly worn may be roughened with a burr to promote the growth of new cartilage - a fibrocartilage material that is similar scar tissue. Debridement of the knee using the arthroscope is not 100% successful. If successful, IT USUALLY AFFORDS TEMPORARY RELIEF of symptoms for somewhere BETWEEN 6 MONTHS - 2 YEARS.
OA Disease Management
OA is a condition which progresses slowly over a period of many years and cannot be cured Treatment is directed at decreasing the symptoms of the condition, and slowing the progress of the condition
Functional treatment goals: Limit pain Increase range of motion Increase muscle strength
OA Non-operative Treatments
Pain medications Physical therapy Walking aids Shock absorption Re-alignment through orthotics Limit strain to affected areas
Younger patients sometimes require the surgery (simply because no other acceptable solution is available to treat their condition)
A metal component is fit onto the femur and a plastic bearing is inserted either directly onto the tibia or onto a metal tray which has been fit onto the tibia Recovery time is generally slightly shorter following this kind of surgery.
The End