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Haemophilia
Haemophilia
NOOR SYAFIQAH IZZATI(10DPY0140) Click to edit Master subtitle style NABILAH(10DPY0139) WAN NORASHIKIN(10DPY0155) SAMSUNNISHA(10DPY0146) SHAKILLA(10DPY0143)
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INTRODUCTION
Haemophilia is a rare bleeding disorder in which the blood does not clot normally. person with haemophilia may bleed for a longer time than others after an injury. Bleeding may occur inside our body (internally), especially in our knees, ankles, and elbows. bleeding can damage our organs and tissues and may be life threatening.
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This
HISTORY OF HAEMOPHILIA
Hemophilia
ACQUIRED.
INHERITED ACQUIRED
mean the disorder is passed from parents to children through genes. mean you are not born with disorder but develop it during your lifetime. may have little or no clotting factor.
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They
TYPE OF HEMOPHILIA
Mild Hemophilia Moderate Hemophilia Severe Hemophilia 5 30 % of normal clotting factor 1 5 % of normal clotting factor Less than 1 % of normal clotting factor
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TYPE OF HEMOPHILIA
Hemophilia A
It It
also known as classic hemophilia and happen due to factor VIII(8) deficiency. may be mild , moderate or severe.About 7 out of 10 person will had severe hemophilia A form of the disorder.
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Hemophilia B
Also In
known as Christmas disease and happen due to lack of factor IX(9). about 30% of cases, there is no family history of the disorder and the condition is the result of a spontaneous gene mutation. in about one in 25,000 male births
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Occurring
CAUSES OF HEMOPHILIA
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Chromosomes
come in pairs. Females have two X chromosomes, while males have one X and one Y chromosome. Only the X chromosome carries the genes related to clotting factors. male who has a faulty hemophilia gene on his X chromosome will have hemophilia. A female must have the faulty gene on both of her X chromosomes to have hemophilia, which is very rare. a female has the faulty gene on only one of her X chromosomes, she is a "hemophilia carrier. 4/30/12 Carriers don't have
If
SYMPTOM OF HEMOPHILIA
Excessive
Bleeding
Signs of external bleeding may include: Bleeding in the mouth from a cut or bite or from cutting or losing a tooth Nosebleeds for no obvious reason Heavy bleeding from a minor cut Signs of internal bleeding may include:
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Bleeding
in the Joints
tightness in the joint with no real pain or any visible signs of bleeding. swollen, hot to touch painful to bend. Joint bleeding that isn't treated quickly can damage the joint.
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Bleeding
in the Brain
Long-lasting, painful headaches or neck pain or stiffness Repeated vomiting Sleepiness or changes in behaviour Double vision
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TREATMENT
Replacement
therapy
Preventive or prophylactic on a regular basic to prevent bleeding therapy. less intensive and expensive than preventive therapy. However, there's a risk that bleeding will cause damage before you receive the demand therapy.
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Demand
Home
treatment
Early treatment lowers the risk of complications. Fewer visits to the doctor or emergency room are needed. Home treatment costs less than treatment in a medical care setting. Home treatment helps children accept treatment and take responsibility for their own health.
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R I
Rest rest the affected joint or muscle. Ice use an icepack, cool cloth or other cooling agents to reduce pain and swelling. (Do not apply for more than 10-15 minutes at a time.) Compression apply pressure to the affected area to slow bleeding.
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C If
PHYSIOTHERAPY MANAGEMENT
relieve
stimulating
absorption
intervening improve
in the inflammatory process obtain an appropriate physical condition his life quality and prevent and treat the injuries and their possible consequences.
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REFERENCES
v
Beers MH,Porter RS,et al. The Merck Manual Of Diagnosis and Therapy.18th ed.Whitehouse Station,NJ : Merck Reseach Laboratories; 2006:1085-1086 Collins Pw.Treatment of Acquired Hemophilia J Thromb Haemost.2007;5 (5):893-900 Jones P.Living With Hemophilia,5th Edition,Oxford,UK:Oxford University Press,2002
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Chandy
M.Management of Hemophilia In Developing Countries.Hemophilia 1995:1(Supp 1):44-48 S,Jun Y .The treatment of Hemophilia.biotecnol Lett.2009;31(3):321-8.
Youjin
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