Professional Documents
Culture Documents
Lab Oral Infections (Lab 4)
Lab Oral Infections (Lab 4)
Herpetic whitlow
Intraepithelial vesicle
Chicken pox
Microscopic features: identical to HSV Prognosis for varicella is usually mild in children. vaccine is available. Acyclovir in immunocompro mised
Shingles
Infectious mononucleosis
pharyngitis
lymphadenopathy
petechei
Herpangina
ANUG
Clinically Ulceration of interdental papilla and gingival margins Grey-green psuedomembrane Halitosis, salivation, lymphadenopathy
Actinomycosis
Actinomycosis
Etiology
filamentous branching Commensal organism Diagnosis
Culture, biopsy
Treatment
Long term high dose antibiotics Penicillin or tetracycline
Actinomycosis
neutrophils
Actinomyces colonies
Tzank cells
Syphilis
Clinical features
Primary
Chancre occurs at site of infection and is highly contagious
Syphilis
Clinical features
Secondary
Diffuse painless, maculopapular mucocutaneous rash 30% have grayish mucosal necrosis which are called mucous patches
Syphilis
Treponema pallidum Primary: chancre : shallow ulcer
Indurated base Associated with lymphadenopathy Heals spontanously
Syphilis
Mucous patch
6 weeks later
Secondary syphilis: skin rash and mucous patch Snail track ulcers, flat areas of ulceration that coalesced
Years later
Tertiary :
Gumma:
Necrosis and type IV hypersensitivity Perforation of palate
Atrophic glossitis:
due to endarteritis obliterance Followed by:
Syphilitic leukoplakia
Hyperkeratosis Followed by: Squamous cell carcinoma
Syphilis
Tertiary - Gumma on hard palate
Congenital Syphilis
Miscarriage, still birth or neonatal infection Collapse of nasal bridge Hutchinson triad: blindness, deafness, dental anomalies Hutchinson incisors (notched teeth)
Screw driver teeth
Classical TB ulcer:
Painless Undermind On the tongue
Leprosy
Gonorrhoea
Neisseria gonorrhea Mainly tonsillar and soft palatal lesions Erythema, vesicles, ulcers, pain
White
PAS stain
Neutrophils microabscess
PAS Stain
hyphae
Angular Cheilitis
Fungal or bacterial or combined
Angular Cheilitis
Multifactorial disease of infectious origin
Candida or Staph aureus or Streptoccocci
Blastomycosis
Histoplasmosis
Zycomycosis
Sero-postitive for many years later on Persistent generalized lymphadenopathy AIDS related complex: persisitent pyrexia, lymphadenopathy, diarrhea, weight loss, fatigue and malaise Fully developed AIDS: opportunistic infections, Kaposi sarcoma, non Hodgekins lymphoma.
Hairy Leukoplakia
Vertical white folds on lateral border of the tongue, bilaterally White patch that can not be removed May have smooth flat surface May have candidal hyphae but as secondary
Hairy leukoplakia
Acanthosis Parakeratosis Finger like surface projections of parakeratin Absence of inflammatory cells in epithelium and lamina propria Swollen or balloon cells with prominent cell boundaries in pricke cell layer below parakeratin Perinuclear vaculization, small drak nuclei: koilocyte-like cells
parakeratin
Kaposis Sarcoma
Kaposi sarcoma
Proliferating endothelial cells Cleft like vascular channels Extravasated RBC Inflammation Occasional atypical cells
Later stages more atypical cells Early stages difficult to differentiate it from other vascular lesions
Slit-like vessels
HIV lymphoma